Create a VMware / Hyper-V backup set as usual. For VMware, Run Direct is only applicable to ESXi paid version with CBT feature enabled.
Run Direct is only applicable to local destination backup. When creating a local destination backup, check the Run Direct option.
Backing up to local destination.
If you want to run the backed up VM, select the VM in the Restore section.
Here, you can set how to run the VM. If you don't want to overwrite the original VM, make sure the select "Restore to Alternate Location"
Input the alternate VM host info here.
Make sure you select an alternate storage for restore so as not to overwrite the original VM.
Check the summary of your alternative location info.
The restore will create a new UUID. Click "Yes" to proceed.
The VM will be run when the restore process completes. It'll be done within minutes.
After the restore process completed, you can see that the backed up VM is running on your VM host.